/* ==========================================================================
   SuleimanBioinformaticsAnalysis Stylesheet
   Modern, Scientific, High-Performance, Accessible
   ========================================================================== */

:root {
  /* Dark Mode (Default) */
  --bg-primary: #070b14;
  --bg-secondary: #0c1322;
  --bg-tertiary: #111a2e;
  --bg-glass: rgba(12, 19, 34, 0.85);
  --bg-card: rgba(17, 26, 46, 0.88);
  --bg-card-hover: rgba(24, 37, 65, 0.95);
  --border-subtle: rgba(255, 255, 255, 0.08);
  --border-accent: rgba(56, 189, 248, 0.35);
  --border-glow: rgba(0, 242, 254, 0.45);

  --text-primary: #f8fafc;
  --text-secondary: #94a3b8;
  --text-muted: #64748b;
  --text-white: #ffffff;

  --accent-orange: #f97316;
  --accent-amber: #fb923c;
  --accent-emerald: #10b981;
  --accent-violet: #8b5cf6;
  --accent-purple: #a855f7;
  --accent-cyan: #06b6d4;
  --accent-blue: #38bdf8;
  --accent-pink: #f43f5e;

  --gradient-brand: linear-gradient(135deg, #f97316 0%, #fb923c 25%, #8b5cf6 65%, #10b981 100%);
  --gradient-card: linear-gradient(180deg, rgba(255, 255, 255, 0.03) 0%, rgba(255, 255, 255, 0.005) 100%);
  --gradient-cyan: linear-gradient(135deg, #f97316 0%, #ea580c 100%);
  --gradient-emerald: linear-gradient(135deg, #34d399 0%, #059669 100%);
  --gradient-pink: linear-gradient(135deg, #f43f5e 0%, #be123c 100%);

  --shadow-sm: 0 2px 4px rgba(0, 0, 0, 0.3);
  --shadow-md: 0 8px 24px rgba(0, 0, 0, 0.45);
  --shadow-lg: 0 16px 36px rgba(0, 0, 0, 0.55);
  --shadow-glow: 0 0 25px rgba(0, 242, 254, 0.22);

  --font-sans: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, "Helvetica Neue", Arial, sans-serif;
  --font-mono: ui-monospace, SFMono-Regular, Menlo, Monaco, Consolas, "Liberation Mono", "Courier New", monospace;

  --radius-sm: 8px;
  --radius-md: 14px;
  --radius-lg: 20px;
  --radius-full: 9999px;

  --transition-fast: 0.15s ease;
  --transition-normal: 0.25s ease;
  --transition-slow: 0.4s ease;
}

[data-theme="light"] {
  --bg-primary: #f8fafc;
  --bg-secondary: #ffffff;
  --bg-tertiary: #f1f5f9;
  --bg-glass: rgba(255, 255, 255, 0.88);
  --bg-card: rgba(255, 255, 255, 0.95);
  --bg-card-hover: #ffffff;
  --border-subtle: rgba(0, 0, 0, 0.08);
  --border-accent: rgba(2, 132, 199, 0.35);
  --border-glow: rgba(0, 242, 254, 0.3);

  --text-primary: #0f172a;
  --text-secondary: #475569;
  --text-muted: #64748b;
  --text-white: #0f172a;

  --gradient-card: linear-gradient(180deg, rgba(255, 255, 255, 0.9) 0%, rgba(241, 245, 249, 0.7) 100%);
  --shadow-sm: 0 2px 4px rgba(0, 0, 0, 0.05);
  --shadow-md: 0 8px 24px rgba(0, 0, 0, 0.08);
  --shadow-lg: 0 16px 36px rgba(0, 0, 0, 0.12);
  --shadow-glow: 0 0 20px rgba(14, 165, 233, 0.2);
}

/* Global Reset */
*, *::before, *::after {
  box-sizing: border-box;
  margin: 0;
  padding: 0;
}

html {
  scroll-behavior: smooth;
  font-family: var(--font-sans);
  background-color: var(--bg-primary);
  color: var(--text-primary);
  line-height: 1.6;
  -webkit-font-smoothing: antialiased;
}

body {
  min-height: 100vh;
  position: relative;
  overflow-x: hidden;
}

/* Background Atmosphere */
.bg-atmosphere {
  position: fixed;
  inset: 0;
  pointer-events: none;
  z-index: -1;
  overflow: hidden;
}

.glow-orb {
  position: absolute;
  border-radius: 50%;
  filter: blur(100px);
  opacity: 0.15;
}

.orb-1 {
  width: 500px;
  height: 500px;
  background: var(--accent-orange);
  top: -100px;
  left: -100px;
}

.orb-2 {
  width: 600px;
  height: 600px;
  background: var(--accent-violet);
  top: 40%;
  right: -150px;
}

.orb-3 {
  width: 450px;
  height: 450px;
  background: var(--accent-emerald);
  bottom: -50px;
  left: 20%;
}

/* Layout Utilities */
.container {
  width: 100%;
  max-width: 1240px;
  margin-inline: auto;
  padding-inline: 1.5rem;
}

/* Navbar */
.navbar {
  position: sticky;
  top: 0;
  z-index: 100;
  background: var(--bg-glass);
  backdrop-filter: blur(16px);
  -webkit-backdrop-filter: blur(16px);
  border-bottom: 1px solid var(--border-subtle);
  transition: all var(--transition-normal);
}

.navbar-inner {
  display: flex;
  align-items: center;
  justify-content: space-between;
  height: 72px;
}

.brand-link {
  display: flex;
  align-items: center;
  gap: 0.75rem;
  text-decoration: none;
  font-size: 1.2rem;
  font-weight: 700;
  color: var(--text-primary);
}

.brand-logo-img {
  width: 36px;
  height: 36px;
  border-radius: var(--radius-sm);
  object-fit: cover;
}

.brand-title-accent {
  background: var(--gradient-brand);
  -webkit-background-clip: text;
  -webkit-text-fill-color: transparent;
}

.nav-links {
  display: flex;
  list-style: none;
  gap: 1.25rem;
  align-items: center;
}

.nav-link {
  color: var(--text-secondary);
  text-decoration: none;
  font-size: 0.92rem;
  font-weight: 500;
  transition: color var(--transition-fast);
  padding: 0.4rem 0.6rem;
  border-radius: var(--radius-sm);
}

.nav-link:hover, .nav-link:focus-visible {
  color: var(--accent-cyan);
  background: rgba(56, 189, 248, 0.08);
}

.nav-actions {
  display: flex;
  align-items: center;
  gap: 0.75rem;
}

.btn-icon {
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  color: var(--text-primary);
  width: 40px;
  height: 40px;
  border-radius: var(--radius-full);
  display: flex;
  align-items: center;
  justify-content: center;
  cursor: pointer;
  transition: all var(--transition-fast);
}

.btn-icon:hover {
  border-color: var(--accent-cyan);
  color: var(--accent-cyan);
  box-shadow: var(--shadow-glow);
}

.btn-primary {
  display: inline-flex;
  align-items: center;
  gap: 0.5rem;
  padding: 0.6rem 1.25rem;
  background: var(--gradient-cyan);
  color: #070b14;
  font-weight: 600;
  font-size: 0.9rem;
  border-radius: var(--radius-full);
  text-decoration: none;
  border: none;
  cursor: pointer;
  transition: transform var(--transition-fast), box-shadow var(--transition-fast);
}

.btn-primary:hover {
  transform: translateY(-2px);
  box-shadow: var(--shadow-glow);
}

.btn-secondary {
  display: inline-flex;
  align-items: center;
  gap: 0.5rem;
  padding: 0.6rem 1.25rem;
  background: var(--bg-card);
  color: var(--text-primary);
  font-weight: 600;
  font-size: 0.9rem;
  border-radius: var(--radius-full);
  text-decoration: none;
  border: 1px solid var(--border-subtle);
  cursor: pointer;
  transition: all var(--transition-fast);
}

.btn-secondary:hover {
  border-color: var(--accent-blue);
  background: var(--bg-card-hover);
  color: var(--accent-blue);
}

/* Hero Section */
.hero {
  padding-block: 4.5rem 3rem;
  text-align: center;
}

.hero-badge-container {
  display: flex;
  justify-content: center;
  flex-wrap: wrap;
  gap: 0.5rem;
  margin-bottom: 1.5rem;
}

.badge {
  display: inline-flex;
  align-items: center;
  gap: 0.4rem;
  padding: 0.3rem 0.8rem;
  border-radius: var(--radius-full);
  font-size: 0.8rem;
  font-weight: 600;
  background: rgba(56, 189, 248, 0.12);
  color: var(--accent-cyan);
  border: 1px solid rgba(56, 189, 248, 0.3);
}

.badge-purple {
  background: rgba(168, 85, 247, 0.12);
  color: var(--accent-purple);
  border-color: rgba(168, 85, 247, 0.3);
}

.badge-emerald {
  background: rgba(16, 185, 129, 0.12);
  color: var(--accent-emerald);
  border-color: rgba(16, 185, 129, 0.3);
}

.hero-title {
  font-size: clamp(2.2rem, 5vw, 3.8rem);
  font-weight: 800;
  line-height: 1.15;
  margin-bottom: 1.25rem;
  letter-spacing: -0.02em;
}

.hero-title-gradient {
  background: var(--gradient-brand);
  -webkit-background-clip: text;
  -webkit-text-fill-color: transparent;
}

.hero-subtitle {
  font-size: clamp(1rem, 2vw, 1.2rem);
  color: var(--text-secondary);
  max-width: 840px;
  margin-inline: auto;
  margin-bottom: 2.25rem;
}

.hero-cta {
  display: flex;
  justify-content: center;
  flex-wrap: wrap;
  gap: 1rem;
  margin-bottom: 3.5rem;
}

/* Stats Counter Grid */
.stats-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(170px, 1fr));
  gap: 1.25rem;
  margin-top: 2rem;
}

.stat-card {
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-md);
  padding: 1.5rem 1rem;
  text-align: center;
  transition: all var(--transition-fast);
  backdrop-filter: blur(8px);
}

.stat-card:hover {
  transform: translateY(-3px);
  border-color: var(--border-accent);
  box-shadow: var(--shadow-md);
}

.stat-value {
  font-size: 2rem;
  font-weight: 800;
  color: var(--accent-cyan);
  font-family: var(--font-mono);
  margin-bottom: 0.3rem;
}

.stat-label {
  font-size: 0.85rem;
  color: var(--text-secondary);
  text-transform: uppercase;
  letter-spacing: 0.05em;
  font-weight: 600;
}

/* Architecture Banner */
.architecture-section {
  padding-block: 2.5rem;
}

.architecture-banner {
  background: var(--gradient-card);
  border: 1px solid var(--border-accent);
  border-radius: var(--radius-lg);
  padding: 2rem;
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 2rem;
  box-shadow: var(--shadow-md);
  backdrop-filter: blur(12px);
}

@media (max-width: 768px) {
  .architecture-banner {
    grid-template-columns: 1fr;
  }
}

.arch-col {
  display: flex;
  flex-direction: column;
  gap: 0.75rem;
}

.arch-header {
  display: flex;
  align-items: center;
  gap: 0.75rem;
}

.arch-icon {
  width: 42px;
  height: 42px;
  border-radius: var(--radius-sm);
  display: flex;
  align-items: center;
  justify-content: center;
  font-size: 1.4rem;
}

.arch-icon-web {
  background: rgba(0, 242, 254, 0.15);
  color: var(--accent-cyan);
}

.arch-icon-vault {
  background: rgba(16, 185, 129, 0.15);
  color: var(--accent-emerald);
}

.arch-title {
  font-size: 1.2rem;
  font-weight: 700;
}

.arch-desc {
  color: var(--text-secondary);
  font-size: 0.95rem;
}

.arch-list {
  list-style: none;
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
  font-size: 0.9rem;
}

.arch-list li {
  display: flex;
  align-items: center;
  gap: 0.5rem;
  color: var(--text-muted);
}

.arch-list li::before {
  content: "✓";
  color: var(--accent-cyan);
  font-weight: bold;
}

/* Section Common */
.section {
  padding-block: 4rem;
}

.section-header {
  text-align: center;
  max-width: 720px;
  margin-inline: auto;
  margin-bottom: 2.75rem;
}

.section-tag {
  color: var(--accent-cyan);
  font-size: 0.85rem;
  font-weight: 700;
  text-transform: uppercase;
  letter-spacing: 0.1em;
  margin-bottom: 0.5rem;
  display: block;
}

.section-title {
  font-size: clamp(1.8rem, 3.5vw, 2.5rem);
  font-weight: 800;
  margin-bottom: 0.75rem;
}

.section-desc {
  color: var(--text-secondary);
  font-size: 1.05rem;
}

/* Tabs Navigation */
.tabs-nav {
  display: flex;
  justify-content: center;
  flex-wrap: wrap;
  gap: 0.5rem;
  margin-bottom: 2rem;
}

.tab-btn {
  padding: 0.65rem 1.25rem;
  border-radius: var(--radius-full);
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  color: var(--text-secondary);
  font-size: 0.92rem;
  font-weight: 600;
  cursor: pointer;
  transition: all var(--transition-fast);
}

.tab-btn:hover {
  color: var(--text-primary);
  border-color: var(--border-accent);
}

.tab-btn.active {
  background: var(--gradient-cyan);
  color: #070b14;
  border-color: transparent;
  box-shadow: var(--shadow-glow);
}

/* Tab Panels */
.tab-panel {
  display: none;
  animation: fadeIn 0.3s ease;
}

.tab-panel.active {
  display: block;
}

@keyframes fadeIn {
  from { opacity: 0; transform: translateY(8px); }
  to { opacity: 1; transform: translateY(0); }
}

/* Modern Responsive Table (following modern-web-guidance) */
.table-wrapper {
  overflow: auto;
  max-inline-size: 100%;
  max-block-size: min(560px, 75vh);
  container-type: inline-size;
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-md);
  background: var(--bg-card);
  box-shadow: var(--shadow-md);
}

table {
  width: 100%;
  border-collapse: separate;
  border-spacing: 0;
  font-size: 0.9rem;
  text-align: left;
}

caption {
  padding: 1rem 1.25rem;
  font-weight: 700;
  font-size: 1.05rem;
  text-align: left;
  background: var(--bg-tertiary);
  border-bottom: 1px solid var(--border-subtle);
  color: var(--text-primary);
}

/* Sticky column headers */
thead {
  position: sticky;
  inset-block-start: 0;
  z-index: 2;
  background: var(--bg-secondary);
}

th {
  padding: 0.85rem 1rem;
  font-weight: 600;
  color: var(--text-secondary);
  border-bottom: 1px solid var(--border-subtle);
  white-space: nowrap;
}

td {
  padding: 0.85rem 1rem;
  border-bottom: 1px solid var(--border-subtle);
  color: var(--text-primary);
  vertical-align: middle;
}

tbody tr:hover {
  background: var(--bg-card-hover);
}

/* Sticky row headers on desktop */
tbody th {
  position: sticky;
  inset-inline-start: 0;
  background: var(--bg-card);
  font-family: var(--font-mono);
  font-weight: 700;
  color: var(--accent-cyan);
  z-index: 1;
}

tbody tr:hover th {
  background: var(--bg-card-hover);
}

/* Responsive Stacked Layout via Container Query */
@container (width < 640px) {
  table, thead, tbody, tr, th, td {
    display: block;
  }

  thead {
    display: none;
  }

  tr {
    margin-block-end: 1rem;
    border-bottom: 1px solid var(--border-accent);
    padding: 0.5rem;
  }

  tbody th {
    position: sticky;
    inset-block-start: 0;
    z-index: 2;
    background: var(--bg-tertiary);
    font-size: 1.05rem;
    border-radius: var(--radius-sm);
  }

  td {
    display: flex;
    justify-content: space-between;
    padding: 0.5rem 0.75rem;
    border-bottom: 1px solid rgba(255, 255, 255, 0.04);
  }

  td::before {
    content: attr(data-label) ": ";
    font-weight: 600;
    color: var(--text-secondary);
    margin-right: 1rem;
  }
}

/* Filter Bar */
.filter-bar {
  display: flex;
  flex-wrap: wrap;
  gap: 1rem;
  align-items: center;
  justify-content: space-between;
  margin-bottom: 1.25rem;
  padding: 1rem;
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-md);
}

.search-input {
  flex: 1 1 250px;
  background: var(--bg-secondary);
  border: 1px solid var(--border-subtle);
  padding: 0.6rem 1rem;
  border-radius: var(--radius-sm);
  color: var(--text-primary);
  font-size: 0.92rem;
  outline: none;
  transition: border-color var(--transition-fast);
}

.search-input:focus {
  border-color: var(--accent-cyan);
}

.filter-select {
  background: var(--bg-secondary);
  border: 1px solid var(--border-subtle);
  padding: 0.6rem 1rem;
  border-radius: var(--radius-sm);
  color: var(--text-primary);
  font-size: 0.92rem;
  outline: none;
  cursor: pointer;
}

.filter-count {
  font-size: 0.88rem;
  color: var(--text-secondary);
}

/* Badges for DEGs */
.badge-deg-up {
  display: inline-block;
  padding: 0.2rem 0.55rem;
  border-radius: var(--radius-full);
  font-size: 0.75rem;
  font-weight: 700;
  background: rgba(244, 63, 94, 0.15);
  color: #fb7185;
  border: 1px solid rgba(244, 63, 94, 0.3);
}

.badge-deg-down {
  display: inline-block;
  padding: 0.2rem 0.55rem;
  border-radius: var(--radius-full);
  font-size: 0.75rem;
  font-weight: 700;
  background: rgba(56, 189, 248, 0.15);
  color: #38bdf8;
  border: 1px solid rgba(56, 189, 248, 0.3);
}

/* Figures Grid */
.figures-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(320px, 1fr));
  gap: 1.5rem;
  margin-top: 1.5rem;
}

.figure-card {
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-md);
  overflow: hidden;
  transition: all var(--transition-fast);
  cursor: pointer;
}

.figure-card:hover {
  transform: translateY(-4px);
  border-color: var(--border-accent);
  box-shadow: var(--shadow-lg);
}

.figure-img-wrap {
  position: relative;
  width: 100%;
  height: 240px;
  background: #000;
  overflow: hidden;
}

.figure-img-wrap img {
  width: 100%;
  height: 100%;
  object-fit: contain;
  transition: transform var(--transition-slow);
}

.figure-card:hover .figure-img-wrap img {
  transform: scale(1.04);
}

.figure-meta {
  padding: 1rem 1.25rem;
}

.figure-title {
  font-size: 1rem;
  font-weight: 700;
  margin-bottom: 0.4rem;
  color: var(--text-primary);
}

.figure-desc {
  font-size: 0.85rem;
  color: var(--text-secondary);
}

/* Modal for Image Zoom */
.modal {
  display: none;
  position: fixed;
  inset: 0;
  z-index: 999;
  background: rgba(0, 0, 0, 0.85);
  backdrop-filter: blur(8px);
  align-items: center;
  justify-content: center;
  padding: 1.5rem;
}

.modal.active {
  display: flex;
}

.modal-content {
  max-width: 90vw;
  max-height: 90vh;
  position: relative;
  display: flex;
  flex-direction: column;
  align-items: center;
}

.modal-img {
  max-width: 100%;
  max-height: 80vh;
  object-fit: contain;
  border-radius: var(--radius-md);
  border: 1px solid var(--border-subtle);
}

.modal-caption {
  color: #ffffff;
  margin-top: 1rem;
  font-size: 1.05rem;
  text-align: center;
}

.modal-close {
  position: absolute;
  top: -40px;
  right: 0;
  color: #fff;
  font-size: 2rem;
  background: none;
  border: none;
  cursor: pointer;
}

/* Cards & Callouts */
.cards-2col {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 1.5rem;
  margin-top: 1.5rem;
}

@media (max-width: 768px) {
  .cards-2col {
    grid-template-columns: 1fr;
  }
}

.info-card {
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-md);
  padding: 1.5rem;
}

.info-card-header {
  display: flex;
  align-items: center;
  gap: 0.75rem;
  margin-bottom: 1rem;
}

.info-card-title {
  font-size: 1.15rem;
  font-weight: 700;
}

/* Clinical Banner */
.disclaimer-banner {
  background: rgba(245, 158, 11, 0.1);
  border: 1px solid rgba(245, 158, 11, 0.35);
  border-radius: var(--radius-md);
  padding: 1rem 1.25rem;
  margin-bottom: 1.5rem;
  display: flex;
  align-items: flex-start;
  gap: 0.75rem;
  font-size: 0.9rem;
  color: #fcd34d;
}

/* Footer */
.footer {
  border-top: 1px solid var(--border-subtle);
  background: var(--bg-secondary);
  padding-block: 3.5rem 2rem;
  margin-top: 5rem;
}

.footer-grid {
  display: grid;
  grid-template-columns: 2fr 1fr 1fr;
  gap: 2.5rem;
  margin-bottom: 2.5rem;
}

@media (max-width: 768px) {
  .footer-grid {
    grid-template-columns: 1fr;
  }
}

.footer-brand p {
  color: var(--text-secondary);
  font-size: 0.92rem;
  margin-top: 0.75rem;
  max-width: 400px;
}

.footer-col h4 {
  font-size: 1rem;
  font-weight: 700;
  margin-bottom: 1rem;
  color: var(--text-primary);
}

.footer-links {
  list-style: none;
  display: flex;
  flex-direction: column;
  gap: 0.5rem;
}

.footer-links a {
  color: var(--text-secondary);
  text-decoration: none;
  font-size: 0.9rem;
  transition: color var(--transition-fast);
}

.footer-links a:hover {
  color: var(--accent-cyan);
}

.footer-bottom {
  text-align: center;
  padding-top: 2rem;
  border-top: 1px solid var(--border-subtle);
  color: var(--text-muted);
  font-size: 0.85rem;
}

/* ==========================================================================
   Volcano Plot & Dynamic Scientific Visualization
   ========================================================================== */
.volcano-card {
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-md);
  padding: 1.5rem;
  margin-bottom: 2rem;
  box-shadow: var(--shadow-sm);
}

.volcano-header {
  display: flex;
  justify-content: space-between;
  align-items: flex-start;
  flex-wrap: wrap;
  gap: 1rem;
  margin-bottom: 1.25rem;
}

.volcano-title {
  font-size: 1.2rem;
  font-weight: 700;
  color: var(--text-primary);
}

.volcano-subtitle {
  font-size: 0.9rem;
  color: var(--text-secondary);
  max-width: 650px;
  margin-top: 0.25rem;
}

.volcano-stats-pills {
  display: flex;
  gap: 0.5rem;
  align-items: center;
}

.pill {
  padding: 0.3rem 0.75rem;
  border-radius: var(--radius-full);
  font-size: 0.8rem;
  font-weight: 700;
  font-family: var(--font-mono);
}

.pill-up {
  background: rgba(244, 63, 94, 0.15);
  color: var(--accent-pink);
  border: 1px solid rgba(244, 63, 94, 0.3);
}

.pill-down {
  background: rgba(6, 182, 212, 0.15);
  color: var(--accent-cyan);
  border: 1px solid rgba(6, 182, 212, 0.3);
}

.pill-ns {
  background: rgba(148, 163, 184, 0.15);
  color: var(--text-muted);
  border: 1px solid rgba(148, 163, 184, 0.3);
}

.volcano-controls {
  display: flex;
  align-items: center;
  flex-wrap: wrap;
  gap: 1.5rem;
  padding: 1rem;
  background: var(--bg-tertiary);
  border-radius: var(--radius-sm);
  margin-bottom: 1.25rem;
}

.control-group {
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
  font-size: 0.85rem;
  color: var(--text-secondary);
}

.control-group strong {
  color: var(--accent-orange);
  font-family: var(--font-mono);
}

.slider {
  accent-color: var(--accent-orange);
  cursor: pointer;
  width: 140px;
}

.btn-sm {
  padding: 0.45rem 0.9rem;
  font-size: 0.82rem;
  border-radius: var(--radius-sm);
}

.volcano-chart-wrap {
  position: relative;
  width: 100%;
  overflow-x: auto;
  border-radius: var(--radius-sm);
  background: rgba(7, 11, 20, 0.5);
  border: 1px solid var(--border-subtle);
  padding: 0.5rem;
}

#volcano-svg {
  width: 100%;
  height: auto;
  min-width: 600px;
  display: block;
}

.volcano-tooltip {
  position: absolute;
  background: var(--bg-card);
  border: 1px solid var(--border-accent);
  box-shadow: var(--shadow-md);
  border-radius: var(--radius-sm);
  padding: 0.65rem 0.85rem;
  pointer-events: none;
  font-size: 0.82rem;
  z-index: 50;
  min-width: 170px;
  backdrop-filter: blur(8px);
}

.tooltip-title {
  font-weight: 800;
  font-size: 0.95rem;
  margin-bottom: 0.35rem;
  color: var(--text-primary);
  border-bottom: 1px solid var(--border-subtle);
  padding-bottom: 0.25rem;
}

.tooltip-row {
  display: flex;
  justify-content: space-between;
  gap: 0.75rem;
  margin-bottom: 0.2rem;
  color: var(--text-secondary);
}

/* 3D Structure Viewer Callout & Residue Pills */
.structure-viewer-box {
  background: linear-gradient(135deg, rgba(249, 115, 22, 0.08) 0%, rgba(139, 92, 246, 0.08) 100%);
  border: 1px solid var(--border-accent);
  border-radius: var(--radius-md);
  padding: 1.75rem;
  margin-top: 1.5rem;
  margin-bottom: 2rem;
}

.residues-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(240px, 1fr));
  gap: 1rem;
  margin-top: 1.25rem;
}

.residue-card {
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-sm);
  padding: 1rem;
  display: flex;
  flex-direction: column;
  gap: 0.4rem;
}

.residue-tag {
  font-family: var(--font-mono);
  font-weight: 700;
  font-size: 0.85rem;
  display: inline-block;
  padding: 0.2rem 0.5rem;
  border-radius: var(--radius-sm);
  width: fit-content;
}

.tag-trp80 {
  background: rgba(249, 115, 22, 0.2);
  color: var(--accent-orange);
  border: 1px solid var(--accent-orange);
}

.tag-lys179 {
  background: rgba(6, 182, 212, 0.2);
  color: var(--accent-cyan);
  border: 1px solid var(--accent-cyan);
}

.tag-asp292 {
  background: rgba(168, 85, 247, 0.2);
  color: var(--accent-purple);
  border: 1px solid var(--accent-purple);
}

.sidecar-badge-link {
  display: inline-flex;
  align-items: center;
  gap: 0.5rem;
  background: var(--gradient-brand);
  color: #ffffff;
  padding: 0.6rem 1.25rem;
  border-radius: var(--radius-full);
  font-weight: 700;
  font-size: 0.9rem;
  text-decoration: none;
  box-shadow: var(--shadow-sm);
  transition: transform var(--transition-fast), box-shadow var(--transition-fast);
}

.sidecar-badge-link:hover {
  transform: translateY(-2px);
  box-shadow: var(--shadow-glow);
}

/* Pipeline Flowchart DAG */
.pipeline-dag-container {
  margin-top: 2rem;
  background: var(--bg-card);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-md);
  padding: 1.5rem;
}

.pipeline-dag-steps {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(220px, 1fr));
  gap: 1rem;
  margin-top: 1rem;
}

.dag-step {
  background: var(--bg-tertiary);
  border: 1px solid var(--border-subtle);
  border-radius: var(--radius-sm);
  padding: 1rem;
  display: flex;
  flex-direction: column;
  gap: 0.35rem;
}

.dag-step-number {
  font-size: 0.75rem;
  font-weight: 800;
  color: var(--accent-orange);
  text-transform: uppercase;
  letter-spacing: 0.05em;
}

.dag-step-title {
  font-size: 0.95rem;
  font-weight: 700;
  color: var(--text-primary);
}

.dag-step-tool {
  font-size: 0.8rem;
  font-family: var(--font-mono);
  color: var(--accent-cyan);
}